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Alcohol is one of the most common interactions; alcohol and alprazolam taken in combination have a synergistic effect on one another, which can cause severe sedation, behavioral changes, and intoxication. Other drugs may interact with alprazolam, including prescription and over-the-counter medicines, vitamins, and herbal products. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Archived from the original on 18 December When is Binge Eating a Disorder? Uses Alprazolam is used to treat anxiety and panic disorders. How to use Xanax Read the Medication Guide provided by your pharmacist before you start taking alprazolam and each time you get a refill.