A Moderate Drug Interaction exists between Seroquel and Xanax XR. View detailed information regarding this drug interaction. 5 Answers - Posted in: seroquel, xanax, depression, bipolar disorder on both these medications so I do know how they interact on our bodies. 1 Answer - Posted in: norco, seroquel, xanax, interaction - Answer: Yes, all 3 medicines have similar side effects which will be additive if. What Is The Drug Zyprexa Used For?